Diabetes Pathogenesis
Defective CTLA-4 induction is controlled by gene(s) in Idd5.1 region in nonobese diabetics
Published in Obesity and Diabetes Week, April 3rd, 2006
According to a study from Sweden, "Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), or CD152, is a negative regulator of T-cell activation and has been shown to be associated with autoimmune diseases. Previous work has demonstrated a defect in the expression of this molecule in nonobese diabetic (NOD) mice upon anti-CD3 stimulation in vitro."
"Using a genetic approach," explained M. Lundholm and colleagues, Umea University "we demonstrate that a novel locus (Ctex) telomeric on chromosome I...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Obesity and Diabetes Week
More Articles from Obesity and Diabetes Week
- Cardiovascular Disease
Cardiovascular mortality correlates with obesity in younger men more than in older men - Diabetes Pathogenesis
Diet-induced insulin resistance and obesity susceptibility is mediated by PEPCK overexpression - Insulin Resistance
Hyperphagia may be mediated by developmental perturbations in insulin signaling - Obesity Therapy
Gastric bypass 1-year outcomes for obese youth indicate health benefits offset risks - Obesity Therapy
Group training appears to be more helpful to the participants trying to reduce food portion - Aesthetic Medicine
Body contouring surgery is on the rise - More from this issue of Obesity and Diabetes Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
