Published in Obesity and Diabetes Week, April 3rd, 2006
Study 1: Nonobese diabetic DeltaY1 animals are protected from diabetes development while DeltaX mice remain susceptible.
According to recent research from United Kingdom, "The development of type 1 diabetes in nonobese diabetic (NOD) mice is influenced by major histocompatibility complex (MHC) class II genes. The NOD-E transgenic mouse, which expresses H2-E as a result of the introduction of an Ead gene, is protected from development of type 1 diabetes. While the mechanism of protection remains unclear, the effect has been regarded as a model...
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