Obesity and Diabetes Week
Susan Hasty, Publisher
Table of Contents . . . April 10th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Obesity and Diabetes Week | Other Publications
Endocrinology - Ghrelin secretion is lower in obese, but responds equally to oral glucose in obese and lean
Obesity Complications - Carotid artery stiffness and C-reactive protein were linked to metabolic syndrome in obese
Obesity Complications - Macrophage-secreted factors influence inflammatory and insulin responses in adipocytes
Obesity Epidemiology - Obesity related to insulin resistance adaptation mechanisms are similar across ethnic groups
Obesity Epidemiology - PPARGC1A Gly482Ser polymorphism is linked to high obesity risk in physically inactive
Angiology - Artery stiffness may be predicted by carotid-femoral pulse wave velocity and carotid stiffness
Business Update - AdipoGenix achieves third milestone in deal with Johnson & Johnson
Business Update - Integrated Security Technologies complete acquisition of oral insulin patent application
Business Update - Korean NIH, Affymetrix to collaborate to identify genes associated with critical diseases
Cancer Research - High leptin receptor mRNA expression and leptin levels in breast cancer predicts poor outcome
Cardiology - Cardiovascular risk may be mainly associated with waist circumference in Tehranian women
Cardiology - Coronary heart disease deaths in Ireland halved in 15 years
Cardiology - Obesity-related heart disease may be linked to plasma endothelial cell-specific molecule-1
Clinical Trials - KeraCure initiates multicenter pivotal study of wound healing pack in diabetic foot ulcers
Clinical Trials - Surface Logix initiates phase 1 trial of gastrointestinal-specific MTP inhibitor
Colon Cancer - Colon cancer risk may be associated with central adiposity in women
Complementary & Alternative Medicine - Aloe arborescens Miller components show antidiabetic properties in mouse model
Dental Research - Earlier periodontal treatment leads to lower medical costs
Depression - Racial differences in mental health care in diabetics exist among Medicaid patients
Diabetes Care - Quality of diabetes care requires improvement
Diabetes Complications - Aspirin can inhibit platelet aggregation in most patients with diabetes
Diabetes Complications - Diabetic control, disease duration, and onset age predict diabetes complications risk
Diabetes Complications - EDHF-mediated and endothelium-independent relaxations are impaired in diabetic rat arteries
Diabetes Complications - Gangrenous foot development in diabetes mellitus may involve lipoprotein (a) levels
Diabetes Complications - Glucagon-like peptide 1 administration may reduce cardiovascular risk in type 2 diabetes
Diabetes Complications - Glycoxidation of LDL promotes apoptotic pathways and NFkappaB activation in coronary cells
Diabetes Complications - Nai + increase influences ischemia susceptibility in hearts from diabetic mice
Diabetes Complications - Rat neutrophil function and metabolism is altered considerably by diabetes
Diabetes Control - CareSens meter most precise blood glucose meter with bias of less than 5%
Diabetes Control - Endocrinologist-directed intervention aimed at primary care physicians improves diabetes care
Diabetes Control - Glucose homeostasis regulation involves estrogen receptor-alpha
Diabetes Control - Hypoglycemic medication beliefs among type 2 diabetes mediates success rate
Diabetes Control - In primary care setting few patients achieved diabetes control targets
Diabetes Control - Insulin glargine plus insulin lispro improved glycemic control in type 1 diabetes
Diabetes Control - Insulin glargine plus oral hypoglycemic agents provide glycemic control in type 2 diabetes
Diabetes Diagnosis - Genetic tests can be crucial for correct classification of diabetes type
Diabetes Diagnosis - Primary care practices may improve undiagnosed diabetes detection and improve 1-year outcomes
Diabetes Diagnosis - Retinopathy signs plus a family history of diabetes predict subsequent diabetes risk
Diabetes Education - Diabetes education for youth involving puppets allowed them feel in control of the situation
Diabetes Epidemiology - Benefits of diet in Murcia, Spain do not counteract obesity-related risk factors
Diabetes Epidemiology - EC-SOD gene polymorphism is related to insulin resistance and type 2 diabetes risk
Diabetes Epidemiology - IL-18 promoter polymorphisms are linked to type 1 diabetes predisposition
Diabetes Epidemiology - Interleukin-12p40 gene polymorphism did not seem to play role in type 1 diabetes mellitus
Diabetes Epidemiology - Reports describe recent advances in diabetes epidemiology research
Diabetes Epidemiology - Urinary albumin excretion and renal disease related to diabetes are linked to genetics
Diabetes Management - Healthways announces new agreement with Middle Tennessee Medical Center for diabetes care
Diabetes Pathogenesis - Baroreflex gain are progressively reduced with increasing severity of insulin resistance
Diabetes Pathogenesis - Beta-cell GSIS dysfunction may show fetal survival adaptations that predispose to diabetes
Diabetes Pathogenesis - COX2 (PTGS2) inhibitors augment hexose transport rate in insulin- and AMPK alpha-independent way
Diabetes Pathogenesis - Ca2+ overload and high Ca2+ transport are linked to salivary cell impairment in diabetes
Diabetes Pathogenesis - Decrease in PI-3K/AKT1 survival signaling mediates DN-HNF-1alpha-induced apoptosis
Diabetes Pathogenesis - Diabetes only affects nNOS-containing myenteric neurons without heme oxygenase 2
Diabetes Pathogenesis - Findings describe new data in diabetes pathogenesis research
Diabetes Pathogenesis - Glucagon works to induce ERK 1/2 phosphorylation and raise mesangial cell proliferation
Diabetes Pathogenesis - HNF-4 alpha is essential for glucose stimulated insulin secretion by pancreatic beta-cells
Diabetes Pathogenesis - MCH-/- mice are resistant to aging-associated raises in body weight and insulin resistance
Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis described
Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis detailed
Diabetes Pathogenesis - Phosphorylation of JNK in diabetic rat sensory neurons may impair nerve conduction
Diabetes Pathogenesis - RAS and NOS3 polymorphisms do not seem to influence cardiovascular disease in diabetics
Diabetes Pathogenesis - Rapid infancy weight gain in preterms was slightly related to higher insulin levels
Diabetes Pathogenesis - Recent findings in diabetes pathogenesis provide new insights
Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights
Diabetes Pathogenesis - Researchers detail new studies and findings in the area of diabetes pathogenesis
Diabetes Pathogenesis - Smad7 expression in beta cells disrupts TGF-beta signaling and induces reversible diabetes
Diabetes Pathogenesis - Tissue degeneration in hearts could be caused by increased cell-cycle arrest and DNA repair
Diabetes Pathogenesis - Urinary oxidative stress markers may indicate vascular complication risk in type 1 diabetes
Diabetes Therapy - Salacia oblonga root improves postprandial hyperlipidemia and hepatic steatosis in diabetes
Diabetes Therapy - Behavioral assessment and intervention in pediatric diabetes is reviewed
Diabetes Therapy - Data advance knowledge in diabetes therapy research
Diabetes Therapy - Diabetes mellitus prevalence has increased steadily in Germany to reach 6.45%
Diabetes Therapy - Diabetic nephropathy progression is delayed by probucol
Diabetes Therapy - Duloxetine offers diabetic neuropathy treatment
Diabetes Therapy - Emotional problems in diabetes patients need increased recognition
Diabetes Therapy - Exenatide dose reduced postprandial plasma glucose excursions in type 2 diabetes
Diabetes Therapy - Glycemic control can be achieved with both glargine plus metformin and NPH plus metformin
Diabetes Therapy - Insulin administration route did not alter glucose metabolism
Diabetes Therapy - Insulin aspart was well tolerated and effective during long-term type 1 diabetes treatment
Diabetes Therapy - Insulin release in novel drug delivery system depends on polymer swelling and crosslinking
Diabetes Therapy - Lisinopril plus telmisartan may prevent diabetic nephropathy type 2 diabetes, hypertension
Diabetes Therapy - NCX4016 has protective effect against ischemia-reperfusion injury in diabetic rat hearts
Diabetes Therapy - Okchun-San-C may lower blood glucose level in type 2 diabetic patients
Diabetes Therapy - Pioglitazone raises adiponectin levels and reduces TNF-alpha levels in type 2 diabetics
Diabetes Therapy - Pioglitazone's insulin-sensitizing offers advantage over gliclazide for glycemic control
Diabetes Therapy - Postprandial lipemia in diabetics is restored to normal by insulin sensitization with pioglitazone
Diabetes Therapy - Reports describe recent advances in diabetes therapy research
Diabetes Therapy - Researchers' findings advance diabetes therapy research
Diabetes Therapy - Restenosis in diabetics with coronary lesions was reduced by radiation after stent implant
Diabetes Therapy - Urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats
Diagnostics - Abbott receives U.S. FDA 510K clearance to market blood glucose monitoring system
Diet & Nutrition - Aortic valve disease induced by high fat/high carbohydrate diet in C57BL/6J mice
Diet & Nutrition - Data advance knowledge in diet & nutrition research
Diet & Nutrition - Ghrelin neutralization ameliorates obesity in diet-induced obese mice
Diet & Nutrition - Jenny Craig partners with Penn State nutrition researcher on Volumetrics Cookbook
Diet & Nutrition - Leptin appears to raise renal sympathetic nerve activity and BP after chronic high-fat diet
Diet & Nutrition - Reports advance knowledge in diet & nutrition research
Diet & Nutrition - Studies add new findings to diet & nutrition body of knowledge
Diverticulitis - Recurrent diverticulitis is more likely in obese than in asymptomatic individuals
Drug Delivery - Scientists use wireless MicroChips to control drug release over time
Drug Development - Glibenclamide in single oral dose does not reduce pain-free or maximal walking distance
Drug Development - Takeda selects Lexicon Genetics' hypertension target for development in research alliance
Drug Discovery - CytRx provides 2006 update on RNAi-based drug-discovery programs
Endocrinology - Foxa2 coactivation promotes liver fatty acid oxidation and triglyceride/VLDL secretion
Endocrinology - Gap junction coupled KATP channel activity plays key role in regulating insulin secretion
Endocrinology - Leptin rapidly alters liver triglyceride secretion and lipid oxidative metabolism in vivo
Endocrinology - Rapid Ca2+ uptake by SERCA pump controls insulin secretion amount
Finance - EDiets.com reports Q4 2005 revenues of $12.1 million, up 8.5% from a year ago
Finance - Keryx reports 2005 increase in cash, other assets spurred by common stock offering
Finance - Matria Healthcare reaffirms 2006 revenue estimates to be between $370 to $380 million
Genetics & Genomics - GSTT1 gene may contribute to type 2 diabetes mellitus development
HIV/AIDS Wasting - Weight loss and wasting remain important AIDS-defining conditions
HIV/AIDS-Associated Lipoatrophy - Lipoatrophy improvement in lower extremities is associated with long-term stavudine withdrawal
Healthcare Coverage - Diabetes advocates urge Senate HELP Committee to reject Enzi health insurance legislation
Healthcare Coverage - Healthways expands HealthPlus of Michigan contract to provide disease-management services
Healthcare Coverage - Mutual of Omaha to offer Healthways' myhealthIQ wellness program to group health customers
Heart Failure - Leptin modulates cell size, MMP-2 expression, and collagen profile in human cardiomyocytes
Hyperglycemia - 5-HT reduces hyperphagia in NPY-overexpressing rat through action on 5-HT2A receptors
Hypertension - Hypertension and cardiovascular disease risk are linked to age, diabetes, and albuminuria
Hypertension - In prehypertensives, impaired glucose tolerance raised cardiovascular disease risk
Hypertension - New data illuminates research in hypertension
Information Technology - Invivodata integrates devices for patient-reported data recording in clinical trial
Kidney Transplantation - Findings advance knowledge in kidney transplantation research
Liver Diseases - Non-alcoholic fatty liver disease is increasing among Korean adults
Mergers & Acquisitions - Fisher Scientific expands presence in molecular diagnostics, will acquire Athena Diagnostics
Neuropathic Pain - Lacosamide results statistically significant in diabetic neuropathic pain phase III trial
Non-Alcoholic Steatohepatitis - Non-alcoholic steatohepatitis predictors of fibrosis identified
Obesity Complications - Obesity is an independent risk factor for coronary heart disease mortality
Obesity Epidemiology - Interventions to social environment at community level may offer obesity treatment option
Obesity Epidemiology - Rapid weight gain in infancy and early childhood is adiposity and obesity risk factor
Obesity Epidemiology - Weight gain was linked to sugar-sweetened drink and fatty food intake in Mediterranean cohort
Obesity Pathogenesis - CD11b expression and endothelial cell adhesion in monocytes is linked to high fatty acid levels
Obesity Pathogenesis - Findings in obesity pathogenesis provide new insights
Obesity Pathogenesis - Leptin has a common link to obesity and hypertension
Obesity Pathogenesis - POMC variant implicates beta-MSH in the control of human energy balance
Obesity Pathogenesis - Recent studies add new data to obesity pathogenesis research
Obesity Pathogenesis - Researchers detail new studies and findings in the area of obesity pathogenesis
Obesity Pathogenesis - Researchers provide details of new studies and findings in the area of obesity pathogenesis
Obesity Pathogenesis - Treating adipocytes as endocrine organs is leading to new insights into obesity
Obesity Pathogenesis - p/CIP and SRC-1 play key roles in energy balance by controlling energy intake and expenditure
Obesity Pathogenesis - p38MAPK negatively influences adipogenesis by inhibiting C/EBP beta and PPAR gamma transcription
Obesity Prevention - Obesity prevention in youth needs to involve politics, science, and healthcare
Obesity Surgery - Mayo Clinic researchers say bariatric surgery may reduce risk of heart disease
Obesity Therapy - Botulinum toxin A reduces appetite and may be a potential obesity treatment
Obesity Therapy - Cardiovascular fitness in obese improved by 'Walking for pleasure'
Obesity Therapy - Conservative weight loss is better option for morbid obesity therapy in some patients
Obesity Therapy - Quality of life improved by surgical procedures in severely obese patients
Obesity Therapy - RYGB in high-obesity risk patients was related to a decline in fatty food preference
Obesity Therapy - Total abdominal liposuction followed by abdominoplasty is proposed for massive weight loss
Obstetrics - Birth weight may be associated with maternal glucose levels during third trimester
Obstetrics - Rise in maternal pregestational diabetes corresponds to increased birth complications
Patents - Patent issued to the University of Pittsburgh for 2-methoxyestradiol for diabetes
Pediatric Diabetes - Adolescents with diabetes have friendships that are similar to those among healthy
Personnel - Sirna Therapeutics announces members of scientific advisory board
Physiology - RNA interference-based screen identifies MAP4K4/NIK as a negative regulator
Surgical Technology - Stent registry safety data favors Taxus over Cypher in complex diabetic patients
Transplant Medicine - Novel method may allow transplant of islet cells from single donor into multiple recipients
Type 1 Diabetes - Self-management-based patient education program for hypoglycemia therapy in diabetes is adequate
Type 1 Diabetes - Serum CXCL10 level may be used to assess pathophysiology of type 1 diabetes disease course
Type 2 Diabetes - CytRx's RNAi screening technology supported by publication of scientific article, says company
Type 2 Diabetes - Dopamine D3-RA had a positive effect on renal morphology and albuminuria in type 2 diabetes
Type 2 Diabetes - Gly482Ser variant in PPARGC1 plays a role in type 2 diabetes risk
Type 2 Diabetes - Hypertriglyceridemia, waist-hip ratio, and family T2DM history increase diabetes risk
Type 2 Diabetes - Metformin and TZDs improved fasting hepatic insulin sensitivity and glucose clearance
Type 2 Diabetes - Neuroanatomical framework for the role of the brain in type 2 diabetes was determined
Type 2 Diabetes - Postprandial deterioration of endothelial dysfunction in diabetes is decreased by vitamin C
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