Endocrinology
Rapid Ca2+ uptake by SERCA pump controls insulin secretion amount
Published in Obesity and Diabetes Week, April 10th, 2006
According to recent research published in the journal Endocrinology, "The exocytosis of insulin-containing granules from pancreatic beta-cells is tightly regulated by changes in cytosolic Ca2+ concentration ([Ca2+] i ). We investigated the role of the sarco-endoplasmic reticulum Ca2+-ATPase (SERCA) pump, Na+/ Ca2+ exchanger, and plasma membrane Ca2+-ATPase pump in the Ca2+ dynamics of single rat...
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