Published in Obesity and Diabetes Week, April 10th, 2006
"The melanocortin-4 receptor (MC4R) plays a critical role in the control of energy balance. Of its two pro-opiomelanocortin (POMC)-derived ligands, alpha-and beta-MSH, the majority of attention has focused on alpha-melanocyte-stimulating hormone (MSH), partly reflecting the absence of beta-MSH in rodents," investigators in England report.
Y.S. Lee and colleagues working with the University of Cambridge described, "We screened the POMC gene in 538 patients with severe, early-onset obesity and identified five unrelated probands who were heterozygous...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Obesity and Diabetes Week