Published in Obesity and Diabetes Week, April 10th, 2006
Study 1: The Leu34Phe mutation leads to a putative deficiency in hypothalamic bioactive cocaine- and amphetamine-regulated transcript and may lead to obesity.
According to recent research from the United States, "Cocaine- and amphetamine-regulated transcript (CART) is an anorexigenic neuropeptide synthesized in the hypothalamus. A Leu34Phe missense mutation in proCART has been found in an obese family in humans."
T. Yanik and colleagues at the National Institute of Child Health and Human Development proposed, "Here...
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