Obesity Epidemiology
PPARGC1A Gly482Ser polymorphism is linked to high obesity risk in physically inactive
Published in Obesity and Diabetes Week, April 10th, 2006
"The variant allele of the Gly482Ser polymorphism in peroxisome proliferator-activated receptor-gamma co-activator-1 alpha (PPARGC1A or PGC1 alpha), a critical determinant of skeletal muscle metabolism, has been associated with obesity and type 2 diabetes. Previous studies indicate that these risks depend on sex and environmental triggers such as age," scientists writing in the journal Diabetologia report.
M. Ridderstrale and colleagues at Lund University proposed, "The aim of the present study was to investigate the possible interactions...
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