Published in Obesity and Diabetes Week, April 10th, 2006
Study 1: A nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist reverses endothelial dysfunction in diabetic (db/db-/-) mice.
According to recent research from Canada, "We have previously reported that endothelium-dependent relaxation to acetylcholine is impaired in small mesenteric arteries from spontaneously diabetic (db/db) mice. The objective of the present study was to examine the effects of treatment of the db/db and the insulin-resistant ob/ob mice with the PPAR gamma agonist 2-(2-(4-phenoxy-2-propylphenoxy) ethyl)...
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