Obesity Pathogenesis
Gut peptides and central melanocortin system interactions regulate energy homeostasis
Published in Obesity and Diabetes Week, April 17th, 2006
According to a recent review from the United States, "Genetic and pharmacological studies have shown that the central melanocortin system plays a critical role in the regulation of energy homeostasis."
"Animals and humans with defects in the central melanocortin system display a characteristic melanocortin obesity phenotype typified by increased adiposity, hyperphagia, metabolic defects and increased linear growth. In addition to interacting with long-term regulators of energy homeostasis such as leptin, more recent data suggest that the central...
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