Obesity Epidemiology
Variation in the adiponutrin gene influences its expression and is linked to obesity
Published in Obesity and Diabetes Week, April 24th, 2006
According to recent research from Sweden, "Adiponutrin is one of three recently identified adipocyte lipases. Surprisingly, these proteins also retain transacylase activity, a hitherto unknown pathway of triacylglycerol synthesis in the adipocytes. This may enable them to participate in both anabolic and catabolic processes. The adiponutrin gene (ADPN) is downregulated by fasting and upregulated by refeeding, suggesting a role in lipogenesis."
L.E. Johansson and colleagues working with Lund University determined, "Experiments in human adipocytes confirmed that the...
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