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Diabetic Nephropathy

Adenosine A2A receptor activation soothes inflammation and injury in diabetic nephropathy

Published in Obesity and Diabetes Week, May 1st, 2006

Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy.

According to a study from the United States, "We previously demonstrated the anti-inflammatory effects and renal tissue protection in response to adenosine A2A -receptor (A2A R) activation in acute renal injury. We sought to extend these studies and determine the efficacy of A2A R agonists in a chronic model of renal injury. We hypothesized that A2A agonists mediate renal tissue protection in diabetic nephropathy by reducing glomerular inflammation."

A.S. Awad and colleagues working with the University...

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