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Obesity Epidemiology

ADRB2 gene accounts for obesity-related phenotypes in males

Published in Obesity and Diabetes Week, May 1st, 2006

The ADRB2 gene accounts for a significant part of obesity-related phenotypes in males.

"The potential effect of variants in three catecholaminergic pathway genes (ADRB2, ADRB3, and GNB3) on obesity-related traits was investigated in a European-derived Brazilian population. Three-hundred and thirty-five individuals were screened for the ADRB2 Arg16Gly and Gln27Glu, ADRB3 Trp64Arg, and GNB3 814G->A and 825C->T polymorphisms using PCR-based methods," scientists in Brazil report.

"The association of the polymorphisms with quantitative variables was tested separately in each sex by analysis of covariance using general linear models, including age as...

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