Published in Obesity and Diabetes Week, May 1st, 2006
Study 1: MCH ablation may improve the long-term outcome for several indicators of the aging process.
"Ablation of the hypothalamic peptide, melanin-concentrating hormone (MCH), leads to a lean phenotype and resistance to diet-induced obesity. Observation of MCH-/- mice at older ages suggested that these effects persist in mice >1 year old," scientists writing in the journal Diabetes report.
"Leanness secondary to caloric restriction is known to be associated with improved glucose tolerance as well as an overall...
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