Blood Glucose
AP-2 beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes
Published in Obesity and Diabetes Week, May 8th, 2006
According to a study from Japan, "We have reported the association of variations in the activating protein-2 beta (AP-2 beta) transcription factor gene with type 2 diabetes. This gene was preferentially expressed in 3T3-L1 adipocytes in a differentiation stage-dependent manner, and preliminary experiments showed that subjects with the disease-susceptible allele showed stronger expression in adipose tissue than those without the susceptible allele."
"Thus," proposed Y. Tao and colleagues, Shiga University of Medical Science, "we overexpressed the...
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