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Obesity Pathogenesis

Plasma antioxidant capacity values are impaired in morbidly obese patients

Published in Obesity and Diabetes Week, May 8th, 2006

Plasma antioxidant capacity and corrected antioxidant capacity values are impaired in morbidly obese patients.

"Oxidative stress may play a critical role in the pathogenesis and development of obesity-associated comorbidities. Reactive oxygen and nitrogen species are produced as a consequence of normal aerobic metabolism and removed and/or inactivated in vivo by both endogenous (uric acid, bilirubin, thiols) and diet-derived (exogenous) antioxidants," scientists in Greece report.

J. Melissas and colleagues at the University of Crete conducted the present investigation "to measure the total plasma antioxidant capacity (TAC), as well as the corrected...

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