Obesity & Diabetes Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Obesity & Diabetes Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Genetics & Genomics
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity
May 15th, 2006
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity. According to a study from the United States, "Triglyceride synthesis in most mammalian tissues involves the sequential addition of fatty acids to a glycerol backbone, with unique enzymes required to catalyze each acylation step. Acylation at the sn-2 position requires 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) activity. To date, seven Agpat genes have been identified based on activity and/or sequence similarity, but their physiological functions have not been well established." L. Vergnes and colleagues working with the University of California in Los Angeles...
Source: Obesity & Diabetes Week (2006-05-15)
|
