Published in Obesity and Diabetes Week, May 15th, 2006
Study 1: Prolonged deterioration of endothelial dysfunction in response to postprandial lipemia is attenuated by vitamin C in type 2 diabetes.
"Endothelial dysfunction (ED) has been described in type 2 diabetes (T2DM). We have described previously a diminution of flow-mediated arterial dilatation and, by implication, further ED in T2DM in response to postprandial lipemia (PPL) at 4 h. This is possibly mediated by oxidative stress/alteration of the nitric oxide (NO) pathway. T2DM subjects tend to exhibit both exaggerated and prolonged PPL. We therefore studied the...
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