Obesity & Cardiology
PPAR-agonist improves left ventricular function in obese dyslipidemic mice
Published in Obesity and Diabetes Week, May 15th, 2006
According to recent research published in the journal Arteriosclerosis Thrombosis and Vascular Biology, "We investigated the effect of a dual peroxisome proliferator-activated receptor (PPAR)alpha, gamma-agonist on atherosclerosis and cardiac function in mice with combined leptin and low-density lipoprotein receptor deficiency (DKO). In these mice, obesity, diabetes, and hyperlipidemia are associated with accelerated atherosclerosis and loss of cardiac function."
W. Verreth and...
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