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Obesity Pathogenesis
ENPP1, an insulin receptor inhibitor, is a genetic link between obesity and diabetes
May 15th, 2006
ENPP1, an inhibitor of the insulin receptor, is a genetic link between childhood and adult obesity and type 2 diabetes. According to recent research from France, "Clinical studies have established the strong link between obesity and type 2 diabetes, especially in children, where the rising prevalence of childhood severe obesity has preceded the recent emergence of early-onset forms of 'diabesity'. These data suggested a common genetic background shared by both conditions, which was also supported by the identification by genome scans of several diabesity chromosomal regions of linkage." "The genetic investigation of early-onset form of familial...
Source: Obesity & Diabetes Week (2006-05-15)
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