Diabetes Epidemiology
IL-6-174 G>C polymorphism affects IL-6 levels and insulin resistance link in type 2 diabetes
Published in Obesity and Diabetes Week, May 15th, 2006
"Interleukin-6 (IL-6), a powerful inflammatory mediator, plays a pivotal role in the pathogenesis of insulin resistance and type 2 diabetes. Recently, the IL-6 promoter polymorphism, at position -174 (G>C), has been associated to insulin sensitivity although contrasting data have been reported," scientists in Italy report.
"The aim of this study," proposed R. Testa and colleagues, Istituto di Ricovero e Cura a Carattere Scientifico, "was to evaluate the effect of the IL-6-174G >C polymorphism on insulin...
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