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Antipsychotic Drug Usage & Weight Gain
Metformin did not prevent olanzapine-related body weight gain
May 15th, 2006
Metformin did not prevent olanzapine-related body weight gain. In a recently published article, scientists in Venezuela conducted a study "to assess whether metformin prevents body weight gain (BWG) and metabolic dysfunction in patients with schizophrenia who are treated with olanzapine. Forty patients taking olanzapine (10 mg daily) were randomly allocated to a metformin (n=20; 850 to 1700 mg daily) or placebo (n=20) group in a 14-week double-blind study. Waist circumference (WC), BWG, body mass index (BMI) fasting glucose, insulin, and lipids were evaluated at baseline and at weeks 7 and 14 of treatment." "At week 14, BWG (kg) was similar in the...
Source: Obesity & Diabetes Week (2006-05-15)
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