Diet & Nutrition
Glucose is a critical physiological regulator of feeding in GLUT2-null mouse model
Published in Obesity and Diabetes Week, May 22nd, 2006
"A role for glucose in the control of feeding has been proposed, but its precise physiological importance is unknown. Here, we evaluated feeding behavior in glut2-null mice, which express a transgenic glucose transporter in their beta-cells to rescue insulin secretion (ripglut1;glut2-/- mice)," investigators in Switzerland report.
I. Bady and colleagues at the University of Lausanne explained, "We showed that in the absence of GLUT2, daily food intake was increased and feeding initiation and termination following a fasting period were abnormal. This...
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