Published in Obesity and Diabetes Week, May 22nd, 2006
"Skin injury leads to the release of heme, a potent prooxidant which is degraded by HO-1 to carbon monoxide, iron, and biliverdin, subsequently reduced to bilirubin. Recently the involvement of HO-1 in angiogenesis has been shown; however, the role of heme and HO-1 in wound healing angiogenesis has not been yet investigated," wrote A. Jazwa and colleagues, Jagiellonian University.
"Treatment of HaCaT keratinocytes with hemin (heme chloride) induced HO-1 expression and...
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