Obesity Complications
Increased adrenergic tone may constrain reactive hyperemia in obese Zucker rats
Published in Obesity and Diabetes Week, May 29th, 2006
"Previous studies have demonstrated that skeletal muscle perfusion is impaired in obese Zucker rats (OZR) under control conditions and with elevated metabolic demand versus responses in lean Zucker rats (LZR). To further our understanding of processes contributing to impaired perfusion, we determined whether hyperemic responses following periods of occlusion were altered in skeletal muscle of OZR versus LZR," researchers in the United States report.
J.C. Frisbee at West Virginia University determined, "In isolated hindlimbs, basal blood flow in OZR was less than in LZR,...
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