Published in Obesity and Diabetes Week, July 3rd, 2006
Study 1: Genetic analysis of the diabetes-prone C57BLKS/J mouse strain reveals genetic contribution from multiple strains.
According to recent research from the United States, "The C57BLKS/J (BKS) inbred mouse strain is a widely used animal model of type 2 diabetes. In the presence of the diabetes (db) mutation, obese BKS-db mice develop severe diabetes. Genetic studies of diabetes-susceptibility in this strain are facilitated by the fact that BKS is a genetic composite between the diabetes-resistant C57BL/6J (136) and susceptible DBA/2J (DBA) strains. On this basis, it has been...
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