Obesity Pathogenesis
Glucagon-like peptide-1 and peptide YY improved after gastric bypass in morbidly obese
Published in Obesity and Diabetes Week, July 3rd, 2006
"The mechanisms underlying weight loss after Roux-en-Y gastric bypass (RYGBP) are not well understood. The objective of the study was to assess the changes in active glucagon-like peptide 1 (GLP-1) and total peptide YY (PYY) after RYGBP and examine their relationship with changes in hunger and satiety. This was a prospective study on the changes in active GLP-1, PYY, hunger, and satiety in response to a standardized test meal in nine normal-glucose-tolerant obese subjects [body mass index (BMI) 47.4±6.1 kg/m2] before and 6 wk after RYGBP,"...
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