Obesity and Diabetes Week

Diabetes Therapy - Candesartan protects beta-cell function in diabetes mouse model

Diabetes Therapy - Estradiol improves glucose tolerance and insulin sensitivity in ob/ob mice

Obesity & Diabetes Pathogenesis - Fat and glucose regulate pyruvate dehydrogenase kinase mRNA in pancreatic islets

Obesity Epidemiology - Prenatal nutrition shapes obesity risk through changes in leptin sensitivity

Obesity Pathogenesis - Inhibin beta B expression is high in adipocytes and may correlate to metabolic disease risk

Adenocarcinomas - High body mass index increases adenocarcinoma risk in the esophagus or gastric cardia

Angiography & Diabetes - Acetylcysteine provides no added benefit in diabetes patients with coronary angiography

Arteriogenesis - Hypercholesterolemia lowers arteriogenesis more strongly than hyperglycemia or hyperinsulinemia

Awards - Aetna is named a best employer for healthy lifestyles for a second year

Awards - Karmeen Kulkarni receives ADA Rachmiel Levine Medal for Service

Bariatrics - Severe steatosis after surgery is strongly related to insulin resistance

Business & Finance - CoGenesys raises $55 million in Series A financing

Business Update - Tercica signs distribution agreements to sell IGFD drug in Arab Gulf countries and Taiwan

Cardiac Medical Devices - Data from large registry show excellent outcomes for TAXUS Stent System in diabetic patients

Cardiology - Glucagon-like peptide-1 reduces heart contractility, but raises myocardial glucose uptake

Cardiology - Rimonabant may improve multiple management of cardiometabolic risk factors

Cardiometabolic Risk - Cardiometabolic risk reaches crisis point in U.S.

Cardiovascular Disease - Cardiovascular disease risk pattern is assessed for metabolic syndrome and diabetes

Cardiovascular Disease - Cardiovascular risk factors cluster in the metabolic syndrome

Cardiovascular Disease - Metabolic risk factors in Japanese women consuming traditional diet was examined

Complementary & Alternative Medicine - Consumers seek natural alternatives for joint pain, inflammation as NSAID side effects mount

Diabetes & Cardiovascular Disease - Genetic determinants of metabolic syndrome may be modified by dietary fatty acids

Diabetes & Obesity - Social capital is protective against obesity and diabetes

Diabetes Complications - Angiogenic changes prompt maculopathy after diabetic cataract removal

Diabetes Complications - Antidepressants are associated with increased risk of diabetes in pre-diabetics

Diabetes Complications - Delayed remyelination observed in diabetic rats after ethidium bromide injection in the brainstem

Diabetes Complications - Diabetes mellitus is not related to muscle size and strength in dialysis therapy

Diabetes Complications - Iron-binding antioxidant capacity is impaired in diabetes mellitus

Diabetes Complications - Simple linear model is fit for metabolic risk factor impact on coronary heart disease

Diabetes Control - Diabetes mellitus family caregivers' impact patient quality of life

Diabetes Control - High physical activity and low saturated fat intake is linked to reduced diabetic mortality

Diabetes Control - RAND assessment developed schemes for in-hospital or hospital-based home care services

Diabetes Diagnostics - Study shows light device screens diabetes more accurately than fasting plasma glucose test

Diabetes Models - Diabetes-related bladder and erectile dysfunction can vary in streptozotocin diabetic rat model

Diabetes Pathogenesis - CCAAT/enhancer-binding protein-alpha plays key role in hepatic glucose/lipid homeostasis

Diabetes Pathogenesis - Diabetes-induced peripheral sensitization could be due to local peripheral CCK-8 release

Diabetes Pathogenesis - Group B coxsackievirus diabetogenic phenotype correlates with replication efficiency

Diabetes Pathogenesis - Monocyte CCR2 and monocyte chemoattractant protein-1 expression is raised in diabetes mellitus

Diabetes Pathogenesis - Renal calcium and magnesium transporter abundance is higher in streptozotocin-induced diabetic rat

Diabetes Pathogenesis - Switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells

Diabetes Prevention - Betel-quid chewing reduces metabolic syndrome risk in men

Diabetes Prevention - Body weight reduction intervention in adults reduced type 2 diabetes risk factors

Diabetes Prevention - Glipizide improves glucose and insulin metabolism in impaired glucose tolerance

Diabetes Research - CombinatoRx presents preclinical data on CRx-401, a novel insulin sensitizer

Diabetes Research - Data on AIR Inhaled Insulin System presented at American Diabetes Association meeting

Diabetes Research - Doctors are failing to intensify needed therapy in people with diabetes

Diabetes Therapy - Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice

Diabetes Therapy - Aldose reductase inhibition alters nodal Na⁺ currents and nerve conduction in diabetics

Diabetes Therapy - Byetta study shows sustained improvements in blood glucose control, progressive weight loss

Diabetes Therapy - Ciprofibrate increases paraoxonase activity in patients with metabolic syndrome

Diabetes Therapy - Diabetes fades when an implanted neovascularized device receives pancreatic islets

Diabetes Therapy - Lipid lowering drug therapies reduce cardiovascular risk in diabetics and non-diabetics

Diabetes Therapy - Study shows insulin detemir effectively treats diabetes safely without causing weight gain

Diabetes Therapy - Thiazolidinediones and rexinoids induce (PGC)-1 alpha gene transcription

Diabetes Therapy - Tyrosine phosphatase PTP-MEG2 is hepatic insulin signaling antagonist

Diabetic Neuropathy - Sangamo reports encouraging phase 1b clinical data on diabetic neuropathy drug at ADA meeting

Diagnostics - Abbott's investigational glucose monitoring system shows promise in new studies

Diet & Nutrition - Asian-style diets increase glucose dysregulation after switch to Western-style diet

Diet & Nutrition - Carbohydrate restriction and weight loss provide equal atherogenic dyslipidemia benefits

Disaster Preparedness - American Diabetes Association creates disaster guide for people with diabetes

End Stage Renal Disease - End-stage renal disease patients with raised cardiac troponin T levels have high mortality

Endocrinology - Free fatty acids decrease circulating ghrelin levels in humans

Endocrinology - Glucose and insulin counteract inhibitory actions of fatty acids on hepatic glucose uptake

Endocrinology - Neuropeptide ligand of G protein-coupled receptor GPR103 regulates feeding and blood pressure

Endocrinology - Phosphoinositide 3-kinase pathway is critical for insulin's actions in the liver

Facilities - American Diabetes Association launches in silico diabetes research center

Fitness & Wellness - Cheap pedometers should not be used for public health measures, warn doctors

Fitness & Wellness - Choices and a stimulating environment improved attendance of diet and exercise interventions

Fitness & Wellness - Exercise-induced increases in SOCS-3 expression in skeletal muscle may raise IL-6 expression

Gastroenterology - Gastroesophageal reflux is associated with even moderate weight increase in women

Genetics & Genomics - Insomnia, sleepiness, and obesity are under strong genetic influence

Genetics & Genomics - PGC-1alpha variants with Gly/Gly at 482nd amino acid may impair Tfam transcription

Genetics & Genomics - PPAR N-terminal domain controls isotype-selective gene expression and adipogenesis

HIV/AIDS HAART - HIV/AIDS patients on efavirenz therapy have high-density lipoprotein cholesterol increase

Hepatitis C Virus - Chronic hepatitis C management involves control of metabolic factors

Hyperglycemia - High blood glucose levels associated with increased mortality in intensive care units

Hyperinsulinemia - Hyperinsulinemia is linked to high production rate of apoB-48-containing lipoproteins

Hypertension - Leptin plays a key role in blood pressure regulation and arterial hypertension

Insulin Resistance - N-Gene Research reports positive phase 2 results with insulin sensitizer that corrects mitochondria

Medical Devices - Medidur studies approved for diabetic macular edema

Natural Products - High throughput screening of neuropeptide FF2 receptor ligands may reveal anti-obesity drugs

Nonalcoholic Fatty Liver Disease - Orlistat improves alanine transaminase levels and steatosis in nonalcoholic fatty liver disease

Obesity & Cardiology - Obesity-related cardiac defects may be linked to NADPH oxidase activity and oxidative stress

Obesity & Hypertension - Adiponectin replenishment ameliorates obesity-related hypertension

Obesity Complications - Obesity and surgery risk increased the risk for surgical site infection

Obesity Complications - Obesity directly contributes to suppression of growth hormone synthesis and release

Obesity Complications - Obesity increases survival and decreases transplantation need in ESRD population

Obesity Complications - Resistin may be a modulator of insulin action in the daily feeding/fasting rhythm

Obesity Control - Impact of Weight on Quality of Life-Lite questionnaire is reliable and valid measure

Obesity Epidemiology - Breastfeeding offers a modest protective effect against obesity in adolescence

Obesity Epidemiology - n-6 polyunsaturated fatty acid levels are increasing in the modern diet

Obesity Epidemiology - Obesity risk is enhanced by poor physical activity and strong family history in students

Obesity Epidemiology - Overweight and obesity are not related to macro- and micronutrient intake among adolescents

Obesity Epidemiology - Pc1 mutant mice developed obesity, hyperphagia and high metabolic efficiency

Obesity Pathogenesis - Acylation-stimulating protein levels are higher in preobese interleukin-6-deficient mice

Obesity Pathogenesis - Adiponectin is an important determinant of ApoA-I catabolism

Obesity Pathogenesis - Angiotensin II type 2 receptor agonist inhibits proximal tubule activity in obese model

Obesity Pathogenesis - Brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis

Obesity Pathogenesis - Ghrelin secretion is directly stimulated by neural sympathetic nerves

Obesity Pathogenesis - Growth hormone plays key role in energy balance and nutrient partitioning

Obesity Pathogenesis - Peanut oil elicits weak compensatory dietary response among overweight compared with lean

Obesity Pathogenesis - RFamide peptide QRFP43 causes obesity with hyperphagia and reduced thermogenesis in mice

Obesity Pathogenesis - STAT5 activators modulate acyl CoA oxidase expression in adipocytes

Obesity Research - Food insecurity associated with obesity and diabetes, a new study finds

Obesity Research - Physicians are nervous to talk to parents about Children's weight issues

Obesity Surgery - Post bariatric surgery body contouring procedures are on the rise in U.S.

Obesity Therapy - Arena's lorcaserin phase IIb study results demonstrate significant weight loss