Published in Obesity and Diabetes Week, July 10th, 2006
"Type 1 diabetes is an autoimmune disease influenced by multiple genetic loci. Although more than 20 insulin-dependent diabetes (Idd) loci have been implicated in the nonobese diabetic (NOD) mouse model, few causal gene variants have been identified," wrote S. Kissler and colleagues, Massachusetts Institute of Technology (MIT).
"Here we show that RNAi can be used to probe candidate genes in this disease model. Slc11a1...
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