Cardiology
Glucagon-like peptide-1 reduces heart contractility, but raises myocardial glucose uptake
Published in Obesity and Diabetes Week, July 10th, 2006
According to a study from the United States, "Recent evidence suggests that glucagon-like peptide-1 (GLP-1) enhances recovery of left ventricular (LV) function after transient coronary artery occlusion. However, it is uncertain whether GLP-1 has direct effects on normal or ischemic myocardium and whether the mechanism involves increased myocardial glucose uptake."
T.C. Zhao and colleagues working with the Allegheny General Hospital explained, "LV function and myocardial glucose uptake and lactate production were measured under basal conditions...
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