Diabetes Therapy
Estradiol improves glucose tolerance and insulin sensitivity in ob/ob mice
Published in Obesity and Diabetes Week, July 10th, 2006
According to a study from Sweden, "In this study, we used ob/ob mice as a model to investigate the effects of long-term estradiol administration on insulin sensitivity and to explore the mechanisms that underlie the antidiabetic effects of estrogen on mouse liver. Female ob/ob mice were randomly divided into two groups and given estradiol (100 mcg/kg-d) or vehicle alone for 4 wk."
H. Gao and colleagues at Karolinska Institute determined, "Estrogen administration improved glucose tolerance and insulin response to glucose in ob/ob mice. Moreover, insulin resistance...
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