Weight Loss
Cobalt protoporphyrin-induced weight loss linked to low hypothalamic NO synthase activity
Published in Obesity and Diabetes Week, July 24th, 2006
According to recent research from the United States, "Administration of cobaltic protoporphyrin IX (CoPP) into the third ventricle of the brain by intracerebroventricular injection in rodents is known to result in transient hypophagia and remarkably prolonged weight loss. The mechanism of action of CoPP in eliciting these effects is unknown."
"It is known that nitric oxide plays a role in food intake and that the hyperphagia that results from a wide variety of genetic, physiological, and pharmacological stimuli can be...
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