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Diabetes Pathogenesis

Apolipoprotein B variants involved in blood glucose and lipid level control in diabetes

Published in Obesity and Diabetes Week, July 24th, 2006

Apolipoprotein B gene variants are involved in the control of blood glucose and lipid levels in diabetes.

"We have examined the frequency of the EcoRI, XbaI and MspI RFLPs of the apolipoprotein B (apo 13) gene in 110 type 2 diabetic patients and 91 healthy control subjects in order to ascertain whether variation in this gene may influence the development of non-insulin dependent diabetes mellitus (type 2 diabetes). Serum lipids including total-cholesterol (T-Chol), triacylglycerol (TAG), apolipoprotein E (apo E), apolipoprotein Al (apo Al), apolipoprotein B and lipoprotein (a) (Lp(a)) were analyzed," scientists in Turkey report.

B.S. Duman and...

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