Diabetes & Obesity
Calpain-10 polymorphisms contribute to diabetes risk by regulating abdominal obesity
Published in Obesity and Diabetes Week, July 31st, 2006
"The mechanisms by which the calpain-10 gene (CAPN10) affects the risk of type 2 diabetes are unclear. Therefore, we investigated the effects of four polymorphisms in CAPN10 (single nucleotide polymorphism [SNP]-43, SNP-44, Insertion/Deletion [Indel]-19 and SNP-63) on insulin secretion, insulin action and abdominal fat distribution in offspring of patients with type 2 diabetes," researchers in the United States report.
J. Pihlajamaki and colleagues working with the Joslin Diabetes Center explained, "Insulin secretion was...
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