Published in Obesity and Diabetes Week, August 7th, 2006
Study 1: Kidney pathology is restricted in diabetes models treated with an isocoumarin.
According to a study from Japan, "One of the mechanisms involved in the progression of diabetic nephropathy, the most common cause of end-stage renal failure, is angiogenic phenomenon associated with the increase of angiogenic factors such as vascular endothelial growth factor (VEGF)-A and angiopoietin (Ang)-2, an antagonist of Ang-1."
"In the present study, we examined the therapeutic efficacy of 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid...
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