Diabetes Epidemiology
11482G>A variant in perilipin gene linked to rosiglitazone-related weight gain in diabetes
Published in Obesity and Diabetes Week, August 7th, 2006
"The aim of this study was to examine the effects of perilipin gene (PLIN) polymorphisms on weight gain with rosiglitazone treatment in patients with type 2 diabetes. A total of 160 type 2 diabetic patients were treated with rosiglitazone (4 mg/day) for 12 weeks in addition to their previous medications, which were unchanged. Four single nucleotide polymorphisms (SNPs) at the PLIN locus were genotyped: PLIN 6209T >C, PLIN 11482G >A, PLIN 13041A >G, and PLIN 14995A >T," scientists in South Korea report.
E.S....
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