Obesity & Coronary Heart Disease
Obesity may modify the link between hepatic lipase gene and coronary heart disease risk
Published in Obesity and Diabetes Week, August 7th, 2006
"The -514 C to T polymorphism of the hepatic lipase gene (LIPC) has been associated with lowered LIPC activity and elevated HDL-cholesterol concentrations. Previous findings on the association of this polymorphism with the risk of CHD are inconsistent. Moreover, data on this association among diabetic patients are limited. We investigated the association of the LIPC polymorphism with CHD risk among U.S. diabetic men and evaluated whether this association was modified by adiposity status," investigators in the United States report.
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