Obesity Drug Research
Positive results reported from study of neuropeptide Y5 receptor antagonist in obesity
Published in Obesity and Diabetes Week, August 7th, 2006
The unique mechanism of action of S-2367 involves blocking receptor binding of neuropeptide Y (NPY), a neurotransmitter involved in regulation of energy balance and food consumption. NPY levels are particularly elevated in reduced weight or food deprived subjects, resulting in stimulation of food intake. S-2367 was designed to counteract elevated NPY levels, thereby promoting weight loss and continued weight loss maintenance.
Shionogi assessed the safety and...
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