Diabetes Pathogenesis
Calcineurin A alpha loss results in altered aquaporin 2 function and kidney complications
Published in Obesity and Diabetes Week, August 14th, 2006
"The serine/threonine phosphatase calcineurin is an important signaling molecule involved in kidney development and function. One potential target of calcineurin action is the water channel aquaporin 2 (AQP2). In this study, we examined the effect of loss of calcineurin A alpha (CnA alpha) on AQP2 function in vivo," researchers in the United States report.
J.L. Gooch and colleagues at Emory University found, "CnA alpha null mice were found to have defective postnatal urine-concentrating ability and an impaired urine-concentrating response...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Obesity and Diabetes Week
More Articles from Obesity and Diabetes Week
- Diabetes Pathogenesis
Hepatocytes cocultured with fat cells showed cellular insulin resistance - Diabetes Pathogenesis
High C-reactive protein may play a role in insulin resistance and type 2 diabetes development - Diabetes Therapy
Pioglitazone prevents cardiac remodeling in induced type 2 diabetes mellitus - Diabetic Neuropathy
Aspartoacylase upregulation may contribute to diabetic neuropathy in obesity-induced diabetes - Obesity Epidemiology
Interleukin-6 receptor gene variants associated with BMI and metabolic syndrome factors - Adipose Tissue
Subepicardial adipose tissue thickness was not linked to coronary artery disease severity - More from this issue of Obesity and Diabetes Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
