Diabetes Therapy
Pioglitazone prevents cardiac remodeling in induced type 2 diabetes mellitus
Published in Obesity and Diabetes Week, August 14th, 2006
"The agonists of peroxisome proliferator-activated receptor-gamma (PPAR gamma) ameliorate cardiovascular complications associated with diabetes mellitus. We tested the hypothesis that recovery from ailing to failing myocardium in diabetes by PPAR gamma agonist is in part due to decreased matrix metalloproteinase-9 (MMP-9) activation and left ventricular (LV) tissue levels of homocysteine (Hcy)," researchers in the United States report.
W.E. Rodriguez and colleagues at the University of Louisville explained, "C57BL/6J mice were made diabetic (D) by...
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