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Endocrinology

Mash1 is needed for generic and subtype differentiation of hypothalamic neuroendocrine cells

Published in Obesity and Diabetes Week, August 21st, 2006

Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells.

According to recent research from England, "The neuroendocrine hypothalamus regulates a number of critical biological processes and underlies a range of diseases from growth failure to obesity. Although the elucidation of hypothalamic function has progressed well, knowledge of hypothalamic development is poor. In particular, little is known about the processes underlying the neurogenesis and specification of neurons of the ventral nuclei, the arcuate and ventromedial nuclei."

D.E.G. McNay and colleagues working with the National Institute of Medical...

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