Published in Obesity and Diabetes Week, August 28th, 2006
Study 1: Weight loss reduces plasma endothelin-1 concentration in obese men.
According to recent research published in the journal Experimental Biology and Medicine, "Obesity is associated with endothelial dysfunction that may contribute to the development of diabetes, hypertension, and atherosclerosis. Endothelin-1 (ET-1), which is produced mostly by vascular endothelial cells, has potent vasoconstrictor and proliferative activity in vascular smooth muscle cells and, therefore, has been implicated in regulation of vascular tonus and the progression of...
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