Diet & Nutrition
Choline-poor diet aggravates fatty liver but eases insulin resistance and glucose intolerance
Published in Obesity and Diabetes Week, August 28th, 2006
"Liver fat accumulation is proposed to link obesity and insulin resistance. To dissect the role of liver fat in the insulin resistance of diet-induced obesity, we altered liver fat using a choline-deficient diet," investigators in Scotland report.
P.J. Raubenheimer and colleagues at the University of Edinburgh explained, "C57B1/6 mice were fed a low-fat (10% of calories) or high-fat (45% of calories) diet for 8 weeks; during the final 4 weeks, diets were either choline deficient or choline supplemented."
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