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Endocrinology

Melatonin stimulates glucose transport via IRS-1/PI-3-kinase pathway in muscle cells

Published in Obesity and Diabetes Week, August 28th, 2006

Melatonin stimulates glucose transport via insulin receptor substrate-1/phosphatidylinositol 3-kinase pathway in C2 C12 murine skeletal muscle cells.

According to recent research published in the Journal of Pineal Research, "The prevalence of diabetes has exponentially increased in recent decades due to environmental factors such as nocturnal lifestyle and aging, both of which influence the amount of melatonin produced in the pineal gland. The present study investigated the effect of melatonin on signaling pathways of glucose transport in C2 C12 mouse skeletal muscle cells."

"Intriguingly,"...

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