Published in Obesity and Diabetes Week, August 28th, 2006
"The physiological signaling mechanisms that link glucose sensing to the electrical activity in metabolism-regulating hypothalamus are still controversial. Although ATP production was considered the main metabolic signal, recent studies show that the glucose-stimulated signaling in neurons is not totally dependent on this production," scientists in France report.
"Here," proposed C. Leloup and colleagues, Institut L Bugnard, "we examined whether mitochondrial reactive oxygen species (mROS), which are physiologically generated depending on glucose metabolism, may act...
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