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Endurance training in obese improves glucose tolerance and mitochondrial fatty acid oxidation

Published in Obesity and Diabetes Week, August 28th, 2006

Endurance training in obese humans improves glucose tolerance and mitochondrial fatty acid oxidation and alters muscle lipid content.

According to recent research from Australia, "Muscle fatty acid (FA) metabolism is impaired in obesity and insulin resistance, reflected by reduced rates of FA oxidation and accumulation of lipids. It has been suggested that interventions that increase FA oxidation may enhance insulin action by reducing these lipid pools."

"Here," proposed C.R. Bruce and colleagues, Garvan Institute of Medical Research, "we examined the effect of endurance training on rates of mitochondrial FA oxidation, the activity of carnitine...

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