Obesity and Diabetes Week

Diabetes & Obesity Epidemiology - Adiponectin receptor 1 gene has a role in body size but not diabetes risk

Diabetes & Obesity Pathogenesis - MAP kinase phosphatase-1 deficient mice are resistant to diet-induced obesity

Diabetes Pathogenesis - Glycogen synthase kinase-3 inhibition enhances glucose disposal in prediabetic obese rats

Diabetes Pathogenesis - Toll-like receptor 4 activation is associated with insulin resistance in adipocytes

Obesity Pathogenesis - ChREBP deficiency prevents obesity and improves glucose control in mouse model

Adipose Tissue - Ghrelin action in the brain controls adipocyte metabolism

Apoptosis - Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes

Breast Cancer - Bone mineral density is not a reliable prescreening predictor for mammography in women

Business & Finance - Emisphere Technologies announces second quarter financial results

Business & Finance - Inflammation-focused Logical Therapeutics gets seed capital from PA Early Stage Partners

Business & Finance - Interleukin Genetics reports Q2 revenues of $1.3 million

Business Update - City of Hope named a JDRF Islet Cell Transplant Center

Business Update - Consumer demand drives growth and innovation of SPLENDA Sweetener products

Business Update - Diamyd Medical outlicenses gene to Neurologix for treatment of Parkinson disease

Business Update - dLife launches interactive patient management tool for diabetes educators

Business Update - Spherix signs agreement with Anaclim to conduct U.S. phase 3 trial on type 2 diabetes drug

Business Update - U.S. FDA accepts new drug application for MacuSight's ophthalmic drug candidate for wet DME

Cancer Research - PI3-K/Akt kinase signaling components are expressed in endometrioid-type endometrial neoplasms

Cirrhosis - High resistin in cirrhosis linked to proinflammatory state but not insulin resistance

Colon Cancer - Colon cancer risk is associated with body size and abdominal obesity

Diabetes & Heart Disease - Atorvastatin therapy may not improve cardiovascular end points in type 2 diabetes

Diabetes & Obesity - Isoproterenol stimulates MCP-1 expression and secretion in 3T3-L1 adipocytes

Diabetes & Obesity Epidemiology - Reduced caloric intake in low birthweight infants prevents glucose intolerance and obesity

Diabetes & Obesity Epidemiology - Visfatin gene (PBEF1) variation does not influence obesity or type 2 diabetes development

Diabetes & Obesity Therapy - Orlistat improved weight and metabolic control in overweight type 2 diabetics

Diabetes Complications - Diabetic retinopathy featuring vitreous hemorrhage involves matrix enzyme

Diabetes Complications - Glucose control influences glomerular filtration rate and its prediction in diabetics

Diabetes Complications - Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in diabetes

Diabetes Complications - Microvascular disease in type 2 diabetes linked to lower cerebral blood flow velocity

Diabetes Complications - Nonalbuminuric renal insufficiency in diabetes may be related to increased vascular disease

Diabetes Diagnostics - HLA-DQB1 genotyping does not improve diabetes classification in those with islet antibodies

Diabetes Education - Diabetes mellitus patients often need more awareness and knowledge of their condition

Diabetes Epidemiology - ADIPOQ gene promoter variants are associated with a progression toward type 2 diabetes

Diabetes Epidemiology - Antipsychotic treatment increases diabetes risk

Diabetes Epidemiology - Diabetes mellitus increased over time among community-dwelling patients with heart failure

Diabetes Epidemiology - Kir6.2 gene mutations alter fetal and postnatal growth and also cause neonatal diabetes

Diabetes Epidemiology - Newly identified IPF1 binding site mutation in insulin gene promoter may predispose to diabetes

Diabetes Interventions - Diabetes care interventions in socially disadvantaged populations are reviewed

Diabetes Management - Aetna U.S. Healthcare adds Insulet's diabetes management system as a covered product

Diabetes Management - American Diabetes Association supports back-to-school campaign

Diabetes Management - PinnacleHealth receives $252,000 to improve diabetes care for African Americans and Hispanics

Diabetes Model - CD4⁺CD25⁺ T cells prevent diabetes and insulitis in adoptive transfer model in BB rats

Diabetes Monitoring - Continuous glucose monitoring system is just as effective as intermittent monitoring in children

Diabetes Pathogenesis - Acetylcholine receptor antibodies in myasthenia gravis predict diabetes and thyroid disease risk

Diabetes Pathogenesis - Diabetes development in liver transplantation survivors is more likely in males

Diabetes Pathogenesis - Diabetes is linked to serum concentrations of persistent organic pollutants

Diabetes Pathogenesis - Diabetes promotes cardiac stem cell aging and heart failure; p66^Shc gene deletion prevents them

Diabetes Pathogenesis - Diabetes-associated mtDNA mutation A3243G impairs beta cell function-related pathways

Diabetes Pathogenesis - Dipeptidyl peptidase IV inhibition does not eliminate satiety actions of peptide YY

Diabetes Pathogenesis - Exenatide inhibits beta-cell apoptosis by decreasing thioredoxin-interacting protein

Diabetes Pathogenesis - Exogenous nitric oxide inhibits IRS-1 expression in rat hepatocytes and skeletal myocytes

Diabetes Pathogenesis - Gene silencing reveals specialized roles in glucose metabolism

Diabetes Pathogenesis - Hypoadiponectinemia is not linked to proinflammatory state

Diabetes Pathogenesis - Nitric oxide or its superoxide product may contribute to renal COX-2 induction in diabetic rats

Diabetes Pathogenesis - Systolic left ventricular function linked to metabolic control in hypertensive diabetics

Diabetes Pathogenesis - Tumor necrosis factor-alpha induces endothelial dysfunction in prediabetic metabolic syndrome

Diabetes Pathogenesis - Understanding hepatic glucose and lipid metabolism signaling may provide therapy targets

Diabetes Pathogenesis - Understanding type 2 diabetes pathogenesis is key to its prevention and treatment

Diabetes Risk Factors - Hyperglycemia and hypertension are additively linked to type 2 diabetes complication risk

Diabetes Therapy - Diabetics from Veterans Affairs Diabetes Trial showed better adherence to LDL cholesterol goal

Diabetes Therapy - Edaravone eases hydroxyl radical stress and augmented angiotensin II response in diabetic rats

Diabetes Therapy - Pterostilbene increased hepatic enzyme activity in a diabetic rat model

Diabetes Therapy - Thiazolidinedione treatment reduces subclinical atherosclerosis progression in type 2 diabetes

Diabetic Macular Edema - Diabetic macular edema effects may be monitored by fundus-related microperimetry methods

Diabetic Nephropathy - Diabetic nephropathy is related to high albumin and fibrinogen synthesis in type 2 diabetes

Diabetic Neuropathy - Epalrestat, an aldose reductase inhibitor, delayed diabetic neuropathy progression

Diabetic Neuropathy - Vernalis begins enrollment in phase 2a trial of treatment for diabetic neuropathic pain

Diet & Nutrition - Controlling hunger is key to preventing weight gain say nutrition and weight-loss experts

Diet & Nutrition - Intermaxillary fixation for diet control is not effective for long-term weight loss

Diet & Nutrition - Protein and carbohydrates have similar satiating effects despite divergent ghrelin levels

Diet & Nutrition - Vitamin D may play a role in autoimmune diseases

Diet & Nutrition - Women who accept their bodies are more likely to eat healthy

Diet-Induced Obesity - Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle

Endocrinology - Central insulin action in energy and glucose homeostasis is reviewed

Endocrinology - Ghrelin may be involved in insulin secretion and glucose consumption after gastrectomy

Endocrinology - Glucose-dependent insulinotropic polypeptides lose antidiabetic potential after truncation

Endocrinology - Neuromedin U in paraventricular and arcuate nuclei raises nonexercise activity thermogenesis

Endocrinology - Obesity related to hypothalamic tumor treatment is not due to leptin dysregulation

Endocrinology - STAT3 pathway plays a critical role in leptin's metabolic actions

Fitness & Wellness - Exercise training alters FAT/CD36 and carnitine palmitoyltransferase I colocalization

Fitness & Wellness - Exercise training improved insulin sensitivity but not glycemic control in type 2 diabetes

Fitness & Wellness - Inflammation markers are inversely related to physical activity and fitness

Glycemic Control - Glargine effects on glycemic control, hypoglycemia, and quality of life in diabetes is reported

Healthcare Costs - Blue Cross chooses 15 projects to receive Prevention Minnesota funding

Heart Disease - Fatty acids impair insulin regulation of AMPK and insulin cardioprotection after ischemia

Hepatitis B Virus - Chronic hepatitis B infection independently predicts diabetic renal outcome

Hepatitis C Virus - Diabetes affects fibrosis following liver transplantation for hepatitis C

Hypertension - Prehypertension and overweight is common among Israeli adolescents

Insulin Resistance - Dexamethasone-induced insulin resistance altered cardiac fatty acid composition and utilization

Insulin Resistance - IGF-binding protein-1 levels are a potential serum marker of insulin resistance

Insulin Resistance - Serum resistin levels higher in endurance athletes independent of insulin sensitivity

Insulin Resistance - Urotensin II gene and receptor gene haplotypes are linked to insulin resistance

Islet Transplantation - MicroIslet transplantation studies in diabetic primates successful at six months

Kidney Disease - Poor glycemic control is a predictor of prognosis in diabetics on regular hemodialysis

Laparoscopic Gastric Bypass - Laparoscopic gastric bypass is superior to adjustable gastric band in super morbidly obese

Market Analysis - Advancements in insulin delivery poised to revolutionize diabetes management

Menopause - Postmenopausal symptoms may be related to body fat and lipid levels in women

Mental Health - Beck Depression Inventory identifies overweight and obese with depressive symptoms

Mental Health - Exercise helps sustain mental activity as we age

Metabolic Syndrome - Atorvastatin (10 mg/day) improved insulin sensitivity in metabolic syndrome patients

Metabolic Syndrome - Fetal programming affects energy expenditure in adults by mechanisms related to fat-free body mass

Metabolic Syndrome - G protein-coupled receptors may lead to therapeutic interventions for the metabolic syndrome

Nephrogenic Diabetes Insipidus - Vasopressin type-2 receptor and aquaporin 2 role in nephrogenic diabetes insipidus is reviewed

Neurogenic Gastroparesis - Ghrelin accelerated gastric emptying in patients with neurogenic gastroparesis

Obesity & Heart Failure - Changes in ventricular function and filling pressure may raise heart failure risk in obese

Obesity & Renal Disease - Obesity is associated with family history of end-stage renal disease in incident dialysis

Obesity Complications - Electric impedance tomography enables PEEP optimization in morbidly obese

Obesity Complications - Hyperinsulinemic hypoglycemia after gastric bypass is not due to increased beta-cell mass

Obesity Complications - Obesity raises CD68 and TNF-alpha and lowers adiponectin gene expression in adipose tissue

Obesity Epidemiology - Interleukin-1 system gene variants are associated with fat mass in young men

Obesity Epidemiology - Multiple risk factors for obesity identified using a self-report tool

Obesity Pathogenesis - Adiponectin and adiponectin receptors are promising targets to treat obesity-linked diseases

Obesity Pathogenesis - Enhanced neuronal PIP3 signaling causes K_ATP channel activation and leads to obesity

Obesity Research - Being a couch potato may have a biological basis in the brain

Obesity Research - Cellulite may remain a problem for women, even after weight loss