Diabetes
Researchers' data from the United States and Canada advance diabetes research
Published in Obesity and Diabetes Week, September 4th, 2006
Study 1: Sp1/Sp3 binding is linked to cell-specific expression of the glucose-dependent insulinotropic polypeptide receptor gene.
"The physiological effects of glucose-dependent insulinotropic polypeptide (GIP) are mediated through specific receptors expressed on target cells. Because aberrant GIP receptor (GIPR) expression has been implicated in abnormal GIP responses associated with type 2 diabetes mellitus and food-induced Cushing syndrome, we sought to identify factors that regulate the GIPR," scientists writing in the American Journal of Physiology - Endocrinology and...
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