Diabetes
Studies from the United States and Denmark advance knowledge in diabetes research
Published in Obesity and Diabetes Week, September 4th, 2006
Study 1: Dipeptidyl peptidase-4 inhibition with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.
"Inhibitors of dipeptidyl peptidase-4 (DPP-4), a key regulator of the actions of incretin hormones, exert antihyper-glycemic effects in type 2 diabetic patients. A major unanswered question concerns the potential ability of DPP-4 inhibition to have beneficial disease-modifying effects, specifically to attenuate loss of pancreatic beta-cell mass and function," investigators in the United States report.
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