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Diabetes Diagnostics

HLA-DQB1 genotyping does not improve diabetes classification in those with islet antibodies

Published in Obesity and Diabetes Week, September 4th, 2006

HLA-DQB1 genotyping does not improve the classification of diabetes in patients with islet antibodies.

"The World Health Organization considers an aetiological classification of diabetes to be essential. The aim of this study was to evaluate whether HLA-DQB1 genotypes facilitate the classification of diabetes as compared with assessment of islet antibodies by investigating young adult diabetic patients," scientists in Sweden report.

E. Bakhtadze and colleagues at Lund University explained, "Blood samples were available at diagnosis for 1,872 (90%) of the 2,077 young adult patients (aged 15-34 years old) over a 5-year period in the nationwide Diabetes...

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