Obesity and Diabetes Week

Diabetes & Obesity - Chromium (D-Phenylalanine)₃ shows insulin-sensitizing and cholesterol-lowering effects

Diabetes Therapy - Glucagon-like peptide-1 analog improves glucose tolerance in obese diabetic mice

Obesity Risk Factors - Insulin resistance impacts risk for obesity-related metabolic comorbidities in adolescents

Obesity Therapy - Sibutramine plus behavior therapy program reduced BMI and body weight in obese adolescents

Weight Loss - Magenstrasse and Mill procedure combined with Roux-en-Y gastric bypass improves weight loss

Adipose Tissue - Adipose cells functions and proliferations may be regulated by varying immunological mechanism

Adipose Tissue - Tumor necrosis factor-alpha and interleukin-1 beta raise CTRP1 expression in adipose tissue

Antioxidants - Caffeic acid shows antihyperglycemic and antioxidant properties in db/db mice

Atherosclerosis - Capillary isotachophoresis LDL level related to carotid-artery intima-media thickness

Bariatric Surgery - Bariatric surgery may carry a significant risk of nutritional complications

Bariatric Surgery - Diverse range of services can enhance quality of care and patient base in bariatric surgery

Bariatric Surgery - Night eating syndrome may complicate recovery from bariatric surgery

Business Update - Anaclim to conduct U.S. part of phase 3 trial for Naturlose as type 2 diabetes treatment

Cancer Gene Therapy - Breast cancer-associated gene absence increases expression of axis members

Cardiovascular Disease - Growth hormone response to secretagogues was variable in healthy adults

Cardiovascular Disease - Ischemic heart disease, stroke, CVD and mortality risk increased with metabolic risk factors

Cardiovascular Research - Insulin resistance in early teens may predict diabetes and heart disease as adults

Depression - Depression correlates to long sleep duration and increased mortality

Diabetes & Hypertension - Cardioversion benefits may be inversely related to oxidative injury severity in diabetes

Diabetes & Hypertension - Hypertension therapy with hydrochlorothiazide, candesartan, or lisinopril was beneficial

Diabetes & Multiple Sclerosis - Type 1 diabetes associated with multiple sclerosis risk

Diabetes & Obesity - JNK2 isoform is involved in metabolic regulation and obesity risk

Diabetes Complications - Alveolo-capillary permeability evaluation in diabetes improved using aerosol scintigraphy

Diabetes Complications - Diabetes is a risk factor for cognitive impairment in the elderly

Diabetes Complications - Early-onset type 2 diabetes mellitus is related to end-stage renal disease risk and mortality

Diabetes Complications - Erectile dysfunction linked to depression in diabetes patients

Diabetes Diagnosis - CD127 expression inversely correlates with FoxP3 and CD4⁺ T reg cells suppressive function

Diabetes Epidemiology - Type 1 diabetes is not link to intronic CA repeat within CD48 gene or HERV-K18 variants

Diabetes Pathogenesis - ANG II raises contractile responses in aortas from diabetic rats with systemic hyperinsulinemia

Diabetes Pathogenesis - Diabetes progression is hindered by pharmacologic protection against oxidative stress

Diabetes Pathogenesis - High protein diet may impair glucose homeostasis and raise type 2 diabetes risk

Diabetes Pathogenesis - Multiple endocrine neoplasia type 1 related to higher diabetes prevalence

Diabetes Research - Medros to conduct screenings for drugs to treat diabetes and cancer

Diabetes Research - Study aims to determine if schizophrenia is related to type 2 diabetes

Diabetes Therapy -  Solanum lycocarpum restored hemoglobin and hematocrit to normal values in diabetes model

Diabetes Therapy - Acarbose, in addition to existing treatments in type 2 diabetes, improved life expectancy

Diabetes Therapy - Aminoguanidine prevents arterial stiffening in type 2 diabetes rat model

Diabetes Therapy - Bariatric surgery may improve glucose homeostasis and treat type 2 diabetes

Diabetes Therapy - Caraway fruits show cholesterol and triglycerides lowering activities in rat model

Diabetes Therapy - Cilnidipine plus valsartan showed additive effects and reduced albuminuria in type 2 diabetics

Diabetes Therapy - Diabetes care clinics managed by clinical pharmacists attained treatment goals more often

Diabetes Therapy - Metformin and rosiglitazone or pioglitazone is effective for diabetes and metabolic syndrome

Diabetes Therapy - Most quality control strategies produced improvements in glycemic control

Diabetic Neuropathy - U83836E is a potential treatment for diabetic neuropathy

Diabetic Retinopathy - Diabetic retinopathy is not associated with apolipoprotein E gene polymorphisms

Diabetic Retinopathy - Patients with diabetic retinopathy see iris neovascularization regress after receiving bevacizumab

Diet & Nutrition - Chili consumption may attenuate postprandial hyperinsulinemia

Diet & Nutrition - Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in obesity model

Diet & Nutrition - Everyday beliefs about food often run contrary to scientific evidence

Diet & Nutrition - Fish oils, not atorvastatin, change high-density lipoprotein metabolism in obese men

Diet & Nutrition - Long-term immune-enhancing enteral formula use raises serum insulin-like growth factor-I

Diet & Nutrition - Low-carbohydrate diets may raise lipid levels and coronary disease risk

Diet & Nutrition - Organization develops self-test to help dieters identify their relationships with food

Diet & Nutrition - Reduced food intake is seen after stimulation of hepatic glycogen synthesis by dihydroxyacetone

Diet & Nutrition - Spanish team launches study of bacterial strains present in Andalusian goat's cheese

Diet & Nutrition - Weight-related behaviors are transferred from mother to child

Drug Development - Alantos initiates phase I studies with lead compound for type II diabetes

Drug Development - Athersys receives approval to begin phase I trial of obesity drug

Endocrinology - AMP-activated protein kinase may play a role in obesity and type 2 diabetes

Finance - Hoodia Products International reports 161% increase in July revenues

Finance - Sontra Medical reports $1,610,000 net loss in Q2 2006 compared to $1,752,835 a year ago

Finance - Spherix reports revenue of $7.6 million for Q2 2006 up 7% from same period in 2005

Finance - TolerRx raises $35.6 million to advance monoclonal antibody TRX4 in type 1 diabetes

Fitness & Wellness - Aerobic exercise may not affect bone mineral density in obese postmenopausal women

Fitness & Wellness - Coronary flow velocity reserve is related to abdominal fat and low aerobic fitness

Fitness & Wellness - DietDetective.com launches first-ever "Fat Clock"

Fitness & Wellness - Postexercise hemodynamic responses are affected by body composition

Fitness & Wellness - Promoting physical activity in primary care settings is beneficial but should be expanded

Gastroenterology - Laparoscopic Roux-en-Y gastric bypass not linked to histologic changes in bypassed segments

Gastroenterology - Prophylactic cholecystectomy suitable in obese undergoing open gastric bypass

Gastroenterology - Scientists learn more about how roughage keeps you regular

Gene Expression - Decline in exogenous gene expression correlates with plasmid DNA degradation

Healthcare Access - U.K. Biobank gets unanimous backing from international experts after piloting phase

Heart Disease - Impaired fasting glucose does not necessarily increase coronary heart disease risk factors

Heart Disease - Obesity in acute coronary syndrome linked to more aggressive control and improved outcomes

Insulin Resistance - Activating AMP-activated protein kinase in adipose may improve insulin-resistant states

Insulin Resistance - FK614 acts as a selective PPAR gamma modulator with distinct fat cell regulation properties

Insulin Resistance - Metabolic syndrome in rodents can develop after consuming large amounts of fructose

Lipid Research - Piperine can prevent the accumulation of plasma lipids and lipoproteins

Market Analysis - Market share of top 20 selling cardiovascular drugs was US$54.5 billion in 2005, report says

Menopause - Testosterone alone or with estrogen is associated with postmenopausal changes in lipid profile

Metabolic Disorders - AMP-activated protein kinase in liver may provide a strategy for metabolic disorder management

Metabolic Syndrome - Red wine may protect against metabolic syndrome by enhancing nitric oxide synthase function

Metabolic Syndrome - The metabolic syndrome is associated with chronic kidney disease

Multiple Sclerosis - Chromos updates progress on development of CHR-1103 for treatment of multiple sclerosis

Obesity & Mortality - Premature death in women may be associated with moderate obesity at age 18

Obesity & Obstructive Sleep Apnea - Epiglottis shape reflects improvement in upper airway obstruction after weight loss

Obesity & Self-Image - Heavy weight status adversely influences self-image and self-esteem in girls

Obesity & Society - Costs of obesity-related diet and activity patterns are between 3.58 and 8.73% of GNP

Obesity Complications - LOX-1-dependent autophagy in granulosa cells is an alternative of programmed cell death

Obesity Complications - Obesity and weight gain increase cancer risk in men

Obesity Complications - Obesity increases risk of developing musculoskeletal disorders

Obesity Complications - Trocar-wound hernia prevention method is developed for laparoscopic bariatric operations

Obesity Epidemiology - In obese diabetic KK-A^y mice gene expression in the liver varies with time

Obesity Epidemiology - Study explores serving size, social welfare, and our waistlines

Obesity Pathogenesis - Three novel melanocortin-4 receptor gene variants do not appear related to obesity

Obesity Prevention - Obesity intervention within the school system can be improved

Obesity Study - Nastech initiates dose-ranging study of PYY(3-36) nasal spray for obesity

Obesity Surgery - Reoperation after laparoscopic adjustable gastric banding further improves BMI and health

Obesity Therapy - After laparoscopic gastric bypass, intraoperative fluid volume affects nausea and vomiting

Obesity Therapy - Bariatric surgery improved functional capacity during walking

Obesity Therapy - Gastric bypass induces catabolic changes responsible for weight reduction in obese rat model

Obesity Therapy - Gastric electrical stimulation in obesity therapy excites gastric distension-responsive neurons

Obesity Therapy - Ghrelin may not be responsible for weight loss after gastric bypass surgery

Obesity Therapy - Intragastric balloon can introduce surgery to morbidly obese that refuse surgical intervention

Obesity Therapy - Laparoscopic gastric banding has high long-term complication and failure rates

Obesity Therapy - Linoleic acid may prevent weight, fat gain during holidays and with normal aging

Obesity Therapy - Use of Temperament and Character Inventory may improve weight control after gastric banding

Pediatric Obesity - Overweight and obesity should be evaluated by general practitioners and pediatricians

Pediatric Obesity - Overweight status and weight control behaviors in youth are major public health concerns

Personnel - Dr. Luciano Rossetti joins Merck Research Laboratories in key leadership role